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Article

The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes.

RNA (New York, N.Y.) - 1 Nov 2017

McDermott Suzanne M, Stuart Kenneth

Abstract excerpt

Uridine insertion and deletion RNA editing generates functional mitochondrial mRNAs in Trypanosoma brucei, and several transcripts are differentially edited in bloodstream (BF) and procyclic form (PF) cells correlating with changes in mitochondrial function. Editing is catalyzed by three ∼20S editosomes that have a common set of 12 proteins, but are typified by mutually exclusive RNase III KREN1, N2, and N3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28802260
DOI: 10.1261/rna.062786.117
PMCID: PMC5648035

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The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes.PMID 28802260Read ↗

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