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The Architecture of Trypanosoma brucei editosomes

5 Oct 2016

Abstract excerpt

Uridine insertion and deletion RNA editing generates functional mitochondrial mRNAs in Trypanosoma brucei Editing is catalyzed by three distinct ∼20S editosomes that have a common set of 12 proteins, but are typified by mutually exclusive RNase III endonucleases with distinct cleavage specificities and unique partner proteins. Previous studies identified a network of protein-protein interactions among a subset of...

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PMID: 27708162
DOI: 10.1073/pnas.1610177113

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The Architecture of Trypanosoma brucei editosomesPMID 27708162Read ↗

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