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Article

RNA editing in Trypanosoma brucei requires three different editosomes.

Molecular and cellular biology - 1 Jan 2008

Carnes Jason, Trotter James Raffaello, Peltan Adam, Fleck Michele, Stuart Kenneth

Abstract excerpt

Trypanosoma brucei has three distinct approximately 20S editosomes that catalyze RNA editing by the insertion and deletion of uridylates. Editosomes with the KREN1 or KREN2 RNase III type endonucleases specifically cleave deletion and insertion editing site substrates, respectively. We report here that editosomes with KREPB2, which also has an RNase III motif, specifically cleave cytochrome oxidase II (COII)...

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Identifiers

PMID: 17954557
DOI: 10.1128/MCB.01374-07
PMCID: PMC2223309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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