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Article

RNA editing: complexity and complications

25 Jul 2002

Abstract excerpt

RNA editing in Trypanosomatids creates functional mitochondrial mRNAs by extensive uridylate (U) insertion and deletion as specified by small guide RNAs (gRNAs). Editing is catalysed by the multiprotein editosome. Over 20 of its protein components have been identified and additional proteins are likely to function in editing and its regulation. The functions of only a few editosome proteins have been determined....

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Identifiers

PMID: 12139607
DOI: 10.1046/j.1365-2958.2002.03028.x

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