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Article

TET2 expression level and 5-hydroxymethylcytosine are decreased in refractory cytopenia of childhood.

Leukemia research - 1 Oct 2015

Coutinho Diego F, Monte-Mór Bárbara C R, Vianna Danielle T, Rouxinol Soraia T, Batalha Anna Beatriz W, Bueno Ana Paula S, Boulhosa Alice M, Fernandez Teresa S, Pombo-de-Oliveira Maria S, Gutiyama Luciana M, Abdelhay Eliana, Zalcberg Ilana R

Abstract excerpt

Myelodysplastic syndromes (MDS) are myeloid malignancies characterized by ineffective hematopoiesis, dysplasia, peripheral cytopenia and increased risk of progression to acute myeloid leukemia. Refractory cytopenia of childhood (RCC) is the most common subtype of pediatric MDS and has overlapping clinical features with viral infections and autoimmune disorders. Mutations in TET2 gene are found in about 20-25% of...

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Identifiers

PMID: 26277372
DOI: 10.1016/j.leukres.2015.07.005

Genes

TET2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TET2 expression level and 5-hydroxymethylcytosine are decreased in refractory cytopenia of childhood.PMID 26277372Read ↗

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