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Article

Research Advances in the Mutation of TET2 Gene in Myeloid Maligancies.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 10 Oct 2016

Li Rong, Xu Ming-Jiang, Yang Feng-Chun, Zhou Yuan

Abstract excerpt

TET2 gene is a member of TET oncogene family. It has been reported as a tumor suppressor gene with important roles in myelopiesis. Recent studies have shown that TET2 protein takes part in demethylation by converting 5-methylcytosine (5-mc) into 5-hydroxymethylcytosine (5-hmc). Somatic TET2 inactivation leads to abnormal myelopiesis and myeloid malignancies. In this review,the structure and function of TET2 and...

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Source

Identifiers

PMID: 27825418
DOI: 10.3881/j.issn.1000-503X.2016.05.017

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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