Role of TET2 mutations in myeloproliferative neoplasms.

doi:10.1007/s11899-011-0108-8

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Article

Role of TET2 mutations in myeloproliferative neoplasms.

Current hematologic malignancy reports - 1 Mar 2012

Pronier Elodie, Delhommeau François

Abstract excerpt

Recently, 5-hydroxymethylcytosine (5-hmC), the 6th base of DNA, was discovered as the product of the hydroxylation of 5-methylcytosine (5-mC) by the ten-eleven translocation (TET) oncogene family members. One of them, TET oncogene family member 2 (TET2), is mutated in a variety of myeloid malignancies, including in 15% of myeloproliferative neoplasms (MPNs). Recent studies tried to go further into the biological...

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Source

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Identifiers

PMID: 22200996
DOI: 10.1007/s11899-011-0108-8

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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