Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Concordance of next generation sequence-based and sequence specific oligonucleotide probe-based HLA-DRB1 genotyping.

Human immunology - 1 Dec 2015

Lane Julie A, Johnson Jameel R, Noble Janelle A

Abstract excerpt

Next generation sequencing (NGS) of clonally amplified DNA, using Roche 454 technology, was used to genotype HLA-DRB1, DRB3, DRB4, and DRB5 loci (exon 2 only) from a set of 993 samples from newborns with maternally-reported African American ancestry. DRB1 exon 2 was genotyped previously on the sa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotyping Techniques
Share to High-Throughput Nucleotide Sequencing
Share to Histocompatibility Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DRB1 Chains

Share to Oligonucleotide Probes

Share to Reproducibility of Results

Share to Sequence Alignment

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 26247828
DOI: 10.1016/j.humimm.2015.07.235
PMCID: PMC4674296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26247828-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Concordance of next generation sequence-based and sequence specific oligonucleotide probe-based HLA-DRB1 genotyping.PMID 26247828Read ↗

Determining performance characteristics of an NGS-based HLA typing method for clinical applications.Semantic proximity Read ↗

Comparison of sequence‐specific oligonucleotide probe vs next generation sequencing for HLA‐A, B, C, DRB1, DRB3/B4/B5, DQA1, DQB1, DPA1, and DPB1 typing: Toward single‐pass high‐resolution HLA typing in support of solid organ and hematopoietic cell transplant programsSemantic proximity Read ↗

Next generation sequencing to determine HLA class II genotypes in a cohort of hematopoietic cell transplant patients and donors.Semantic proximity Read ↗

Population-agnostic real-time molecular mismatch estimation using rSSO-defined HLA allele strings: minimal impact of allelic discordance with NGS.Semantic proximity Read ↗

Very high resolution single pass HLA genotyping using amplicon sequencing on the 454 next generation DNA sequencers: Comparison with Sanger sequencing.Semantic proximity Read ↗

Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing.Semantic proximity Read ↗

Validation and application of new NGS-based HLA genotyping to clinical diagnostic practice.Semantic proximity Read ↗

Targeted Next-Generation Sequencing for Human Leukocyte Antigen Typing in a Clinical Laboratory: Metrics of Relevance and Considerations for Its Successful Implementation.Semantic proximity Read ↗

A multi-site study using high-resolution HLA genotyping by next generation sequencing.Semantic proximity Read ↗

Assay-dependent discordance in detecting a rare HLA-DPB1 allele: Long-range PCR vs. hybrid capture NGS.Semantic proximity Read ↗

Combining one-step Sanger sequencing with phasing probe hybridization for HLA class I typing yields rapid, G-group resolution predicting 99% of unique full length protein sequences.Semantic proximity Read ↗

Quantitative Assessment of Analytical Ambiguity in Reverse Sequence-Specific Oligonucleotide (rSSO)-Based HLA Typing Platforms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.