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Validation and application of new NGS-based HLA genotyping to clinical diagnostic practice.

HLA - 1 May 2023

Kim Ji Yeon, Lee Seung Yeob, Kim Ga-Gyoung, Song Hae-In, Jang Mi Mi, Lee Chang Seon, Hong Ju Yeon, Shin Myung-Geun, Choi Hyun-Jung

Abstract excerpt

Next-generation sequencing (NGS) has revolutionized clinical genotyping, providing high-resolution HLA genotyping with a low ambiguity rate. This study aimed to develop new NGS-based HLA genotyping (HLAaccuTest, NGeneBio, Seoul, KOREA) on the Illumina MiSeq platform and validate the clinical performance. The analytical performance of HLAaccuTest was validated for 11 loci comprising HLA-A, -B, -C, -DRB1/3/4/5,...

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PMID: 36813562
DOI: 10.1111/tan.15003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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