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Article

Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing.

Human immunology - 1 Jul 2020

Profaizer Tracie, Pole Ann, Monds Cassandra, Delgado Julio C, Lázár-Molnár Eszter

Abstract excerpt

HLA associations have been linked to many diseases and are important for risk assessment of drug hypersensitivity reactions. The increasing number of HLA alleles discovered generated a list of ambiguities that cannot be resolved with the current clinical assays, which commonly include sequence-specific oligonucleotide probe (SSOP) genotyping, and real-time PCR with melting curve analysis. HLA typing by...

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PMID: 32499099
DOI: 10.1016/j.humimm.2020.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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