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Article

Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1.

Molecular immunology - 1 Oct 2015

Stamogiannos Athanasios, Koumantou Despoina, Papakyriakou Athanasios, Stratikos Efstratios

Abstract excerpt

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) generates antigenic peptides for loading onto Major Histocompatibility Class I molecules (MHCI) and can regulate adaptive immune responses. During the last few years, many genetic studies have revealed strong associations between coding Single Nucleotide Polymorphisms (SNPs) in ERAP1 and common human diseases ranging from viral infections to cancer and autoimmunity....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26224046
DOI: 10.1016/j.molimm.2015.07.010

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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