Article
Structural and biochemical insights into the association between ERAP1 polymorphism and autoimmune diseases.
Biochemical and biophysical research communications - 3 Dec 2022
Liu Shuang, Lu Jianghui, Wu Jiaqi, Feng Dongyan, Wang Yanbing, Su Xin, Cao Hao
Abstract excerpt
Autoimmune diseases afflict nearly 10% of the world's population and have a serious impact on survival and quality of life. Unfortunately, the specific pathogenesis of almost all autoimmune diseases is still unclear, with more research findings identifying some key pathogenic genes at the genetic level and several pathogenic inflammatory factor phenotypes. ERAP1 has been suggested as a potential therapeutic...
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