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The Role of Aminopeptidase ERAP1 in Human Pathology—A Review

20 Feb 2024

Abstract excerpt

Aminopeptidases are a group of enzymatic proteins crucial for protein digestion, catalyzing the cleavage of amino acids at the N-terminus of peptides. Among them are ERAP1 (coding for endoplasmic reticulum aminopeptidase 1), ERAP2 (coding for endoplasmic reticulum aminopeptidase 2), and LNPEP (coding for leucyl and cystinyl aminopeptidase). These genes encoding these enzymes are contiguous and located on the same...

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PMID: 38534723
DOI: 10.3390/cimb46030107

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