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Article

Comparison of male versus female responses in the Pig-a mutation assay.

Mutagenesis - 1 May 2015

Labash Carson, Avlasevich Svetlana L, Carlson Kristine, Torous Dorothea K, Berg Ariel, Bemis Jeffrey C, MacGregor James T, Dertinger Stephen D

Abstract excerpt

Validation of the Pig-a gene mutation assay has been based mainly on studies in male rodents. To determine if the mutagen-induced responses of the X-linked Pig-a gene differ in females compared to males, 7- or 14-week old male and female Sprague Dawley rats were exposed to N-ethyl-N-nitrosourea (...

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PMID: 25833915
DOI: 10.1093/mutage/geu055
PMCID: PMC4422866

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RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25833915-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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