Article
Impaired Glucose Metabolism in Mice Lacking the Tas1r3 Taste Receptor Gene.
PloS one - 1 Jan 2015
Murovets Vladimir O, Bachmanov Alexander A, Zolotarev Vasiliy A
Abstract excerpt
The G-protein-coupled sweet taste receptor dimer T1R2/T1R3 is expressed in taste bud cells in the oral cavity. In recent years, its involvement in membrane glucose sensing was discovered in endocrine cells regulating glucose homeostasis. We investigated importance of extraorally expressed T1R3 taste receptor protein in age-dependent control of blood glucose homeostasis in vivo, using nonfasted mice with a...
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