Article
A candidate taste receptor gene near a sweet taste locus.
Nature neuroscience - 1 May 2001
Montmayeur J P, Liberles S D, Matsunami H, Buck L B
Abstract excerpt
The mechanisms underlying sweet taste in mammals have been elusive. Although numerous studies have implicated G proteins in sweet taste detection, the expected G protein-coupled receptors have not been found. Here we describe a candidate taste receptor gene, T1r3, that is located at or near the mouse Sac locus, a genetic locus that controls the detection of certain sweet tastants. T1R3 differs in amino acid...
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