Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of T1R3 in calcium-magnesium taste.

Physiological genomics - 15 Aug 2008

Tordoff Michael G, Shao Hongguang, Alarcón Laura K, Margolskee Robert F, Mosinger Bedrich, Bachmanov Alexander A, Reed Danielle R, McCaughey Stuart

Abstract excerpt

Calcium and magnesium are essential for survival but it is unknown how animals detect and consume enough of these minerals to meet their needs. To investigate this, we exploited the PWK/PhJ (PWK) strain of mice, which, in contrast to the C57BL/6J (B6) and other inbred strains, displays strong preferences for calcium solutions. We found that the PWK strain also has strong preferences for MgCl2 and saccharin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice, Congenic
Share to Food Preferences

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Magnesium

Share to Calcium

Share to Electrophysiology

Share to Receptors, G-Protein-Coupled

Share to Sweetening Agents

Source

Open in PubMed Open full text

Identifiers

PMID: 18593862
DOI: 10.1152/physiolgenomics.90200.2008
PMCID: PMC2519964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of T1R3 in calcium-magnesium taste.PMID 18593862Read ↗

Gene discovery and the genetic basis of calcium consumption.Semantic proximity Read ↗

Positional cloning of the mouse saccharin preference (Sac) locus.Semantic proximity Read ↗

Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.Semantic proximity Read ↗

Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains.Semantic proximity Read ↗

Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene.Semantic proximity Read ↗

A candidate taste receptor gene near a sweet taste locus.Semantic proximity Read ↗

Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.Semantic proximity Read ↗

Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3.Semantic proximity Read ↗

Genetic controls of Tas1r3-independent sucrose consumption in mice.Semantic proximity Read ↗

Genetics of mouse behavioral and peripheral neural responses to sucrose.Semantic proximity Read ↗

Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.Semantic proximity Read ↗

Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.