Article
Genetic controls of Tas1r3-independent sucrose consumption in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2021
Lin Cailu, Tordoff Michael G, Li Xia, Bosak Natalia P, Inoue Masashi, Ishiwatari Yutaka, Chen Longhui, Beauchamp Gary K, Bachmanov Alexander A, Reed Danielle R
Abstract excerpt
We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (Chr) 4 that affects behavioral and neural responses to sucrose. We have named it the sucrose consumption QTL 2 (Scon2), and shown that it corresponds to the Tas1r3 gene, which encodes a sweet taste receptor subunit TAS1R3. To discover other sucrose consumption QTLs,...
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