Genetic controls of Tas1r3-independent sucrose consumption in mice.

doi:10.1007/s00335-021-09860-w

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Article

Genetic controls of Tas1r3-independent sucrose consumption in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2021

Lin Cailu, Tordoff Michael G, Li Xia, Bosak Natalia P, Inoue Masashi, Ishiwatari Yutaka, Chen Longhui, Beauchamp Gary K, Bachmanov Alexander A, Reed Danielle R

Abstract excerpt

We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (Chr) 4 that affects behavioral and neural responses to sucrose. We have named it the sucrose consumption QTL 2 (Scon2), and shown that it corresponds to the Tas1r3 gene, which encodes a sweet taste receptor subunit TAS1R3. To discover other sucrose consumption QTLs,...

Topics

Alleles
Animals
Carbohydrate Metabolism
Chromosome Mapping
Crosses, Genetic
Epistasis, Genetic
Gene Expression Regulation
Genetic Association Studies
Genotype
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Congenic

Quantitative Trait Loci

Quantitative Trait, Heritable

Receptors, G-Protein-Coupled

Species Specificity

Sucrose

Source

Open in PubMed

Identifiers

PMID: 33710367
DOI: 10.1007/s00335-021-09860-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-33710367-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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