Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.

doi:10.1523/JNEUROSCI.4439-03.2004

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Article

Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Mar 2004

Inoue Masashi, Reed Danielle R, Li Xia, Tordoff Michael G, Beauchamp Gary K, Bachmanov Alexander A

Abstract excerpt

Recent studies have shown that the T1R3 receptor protein encoded by the Tas1r3 gene is involved in transduction of sweet taste. To assess ligand specificity of the T1R3 receptor, we analyzed the association of Tas1r3 allelic variants with taste responses in mice. In the F2 hybrids between the C57...

Topics

Alleles
Animals
Behavior, Animal
Choice Behavior
Chorda Tympani Nerve
Chromosome Mapping
Crosses, Genetic
Genetic Linkage
Genetic Variation
Genotype
Ligands
Lod Score
Mice
Mice, Inbred Strains

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurons

Receptors, Cell Surface

Receptors, G-Protein-Coupled

Species Specificity

Source

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Identifiers

PMID: 14999080
DOI: 10.1523/JNEUROSCI.4439-03.2004
PMCID: PMC1400603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-14999080-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.