Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.

Physiological genomics - 19 Dec 2007

Inoue Masashi, Glendinning John I, Theodorides Maria L, Harkness Sarah, Li Xia, Bosak Natalia, Beauchamp Gary K, Bachmanov Alexander A

Abstract excerpt

The Tas1r3 gene encodes the T1R3 receptor protein, which is involved in sweet taste transduction. To characterize ligand specificity of the T1R3 receptor and the genetic architecture of sweet taste responsiveness, we analyzed taste responses of 129.B6-Tas1r3 congenic mice to a variety of chemically diverse sweeteners and glucose polymers with three different measures: consumption in 48-h two-bottle preference...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Feed
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Food Preferences

Share to Mice, Inbred C57BL

Share to Mice, Mutant Strains

Share to Receptors, Cell Surface

Share to Toll-Like Receptor 3

Source

Open in PubMed Open full text

Identifiers

PMID: 17911381
DOI: 10.1152/physiolgenomics.00161.2007
PMCID: PMC2259227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.PMID 17911381Read ↗

Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.Semantic proximity Read ↗

Allelic variation of the Tas1r3 taste receptor gene affects sweet taste responsiveness and metabolism of glucose in F1 mouse hybrids.Semantic proximity Read ↗

Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.Semantic proximity Read ↗

A candidate taste receptor gene near a sweet taste locus.Semantic proximity Read ↗

Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli.Semantic proximity Read ↗

Impaired Glucose Metabolism in Mice Lacking the Tas1r3 Taste Receptor Gene.Semantic proximity Read ↗

Genetic controls of Tas1r3-independent sucrose consumption in mice.Semantic proximity Read ↗

Positional cloning of the mouse saccharin preference (Sac) locus.Semantic proximity Read ↗

Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains.Semantic proximity Read ↗

Genetics of mouse behavioral and peripheral neural responses to sucrose.Semantic proximity Read ↗

Genetic variation in sweet taste receptors and a mechanistic perspective on sweet and fat taste sensation in the context of obesity.Semantic proximity Read ↗

Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.