Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2015

Hisano Yu, Inoue Asuka, Taimatsu Kiyohito, Ota Satoshi, Ohga Rie, Kotani Hirohito, Muraki Michiko, Aoki Junken, Kawahara Atsuo

Abstract excerpt

The lipid mediator sphingosine-1-phosphate (S1P) regulates various physiological and pathological phenomena such as angiogenesis and oncogenesis. Secreted S1P associates with the G-protein-coupled S1P receptors (S1PRs), leading to the activation of downstream signaling molecules. In mammals, five S1prs have been identified and the genetic disruption of a single S1pr1 gene causes vascular defects. In zebrafish,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Fins
Share to Embryonic Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Zebrafish

Source

Identifiers

PMID: 26094551
DOI: 10.1111/gtc.12259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis.PMID 26094551Read ↗

Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning.Semantic proximity Read ↗

The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis.Semantic proximity Read ↗

Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish.Semantic proximity Read ↗

Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis.Semantic proximity Read ↗

The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors.Semantic proximity Read ↗

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.Semantic proximity Read ↗

[Application of CRISPR/Cas9 Gene Editing Technique to Establish S1PR5 Gene Knockout Mice].Semantic proximity Read ↗

Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish.Semantic proximity Read ↗

The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish.Semantic proximity Read ↗

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.Semantic proximity Read ↗

Site-1 protease is required for cartilage development in zebrafish.Semantic proximity Read ↗

In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.