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Article

Maternal or zygotic sphingosine kinase is required to regulate zebrafish cardiogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2015

Mendelson Karen, Lan Yahui, Hla Timothy, Evans Todd

Abstract excerpt

BACKGROUND: The sphingosine 1-phosphate (S1P) signaling pathway regulates zebrafish cardiogenesis, and provides a paradigm for how signaling gradients coordinate collective cell migration across tissue layers. It is known that the S1P transporter (Spns2) functions in extra-embryonic YSL to activate G protein-coupled receptor (S1pr2) signaling in endoderm for deposition of positional cues (integrin, fibronectin,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25997406
DOI: 10.1002/dvdy.24288
PMCID: PMC4520754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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