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Article

DNA repair defects ascribed to pby1 are caused by disruption of Holliday junction resolvase Mus81-Mms4.

DNA repair - 1 Sept 2015

Ölmezer Gizem, Klein Dominique, Rass Ulrich

Abstract excerpt

PBY1 continues to be linked with DNA repair through functional genomics studies in yeast. Using the yeast knockout (YKO) strain collection, high-throughput genetic interaction screens have identified a large set of negative interactions between PBY1 and genes involved in genome stability. In drug sensitivity screens, the YKO collection pby1Δ strain exhibits a sensitivity profile typical for genes involved in DNA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26068713
DOI: 10.1016/j.dnarep.2015.05.006

Genes

MUS81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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