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Article

Genetic network interactions among replication, repair and nuclear pore deficiencies in yeast.

DNA repair - 4 Apr 2005

Loeillet Sophie, Palancade Benoît, Cartron Marina, Thierry Agnès, Richard Guy-Franck, Dujon Bernard, Doye Valérie, Nicolas Alain

Abstract excerpt

The yeast RAD27 gene encodes a functional homolog of the mammalian FEN1 protein, a structure-specific endo/exonuclease which plays an important role in DNA replication and repair. Previous genetic interaction studies, including a synthetic genetic array (SGA) analysis, showed that the survival of rad27Delta cells requires several DNA metabolic processes, in particular those mediated by all members of the...

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Source

Identifiers

PMID: 15725626
DOI: 10.1016/j.dnarep.2004.11.010

Genes

FEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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