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Article

Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers.

G3 (Bethesda, Md.) - 5 Jun 2024

Li Bin-Zhong, Kolodner Richard D, Putnam Christopher D

Abstract excerpt

Cellular pathways that detect DNA damage are useful for identifying genes that suppress DNA damage, which can cause genome instability and cancer predisposition syndromes when mutated. We identified 199 high-confidence and 530 low-confidence DNA damage-suppressing (DDS) genes in Saccharomyces cerevisiae through a whole-genome screen for mutations inducing Hug1 expression, a focused screen for mutations inducing...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38526099
DOI: 10.1093/g3journal/jkae064
PMCID: PMC11152081

Genes

PIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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