Article
Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae.
G3 (Bethesda, Md.) - 5 Oct 2017
Segura-Wang Maia, Onishi-Seebacher Megumi, Stütz Adrian M, Mardin Balca R, Korbel Jan O
Abstract excerpt
To ensure genomic integrity, living organisms have evolved diverse molecular processes for sensing and repairing damaged DNA. If improperly repaired, DNA damage can give rise to different types of mutations, an important class of which are genomic structural variants (SVs). In spite of their importance for phenotypic variation and genome evolution, potential contributors to SV formation in Saccharomyces...
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