Article
Mutability and mutational spectrum of chromosome transmission fidelity genes.
Chromosoma - 1 Jun 2012
Stirling Peter C, Crisp Matthew J, Basrai Munira A, Tucker Cheryl M, Dunham Maitreya J, Spencer Forrest A, Hieter Philip
Abstract excerpt
It has been more than two decades since the original chromosome transmission fidelity (Ctf) screen of Saccharomyces cerevisiae was published. Since that time the spectrum of mutations known to cause Ctf and, more generally, chromosome instability (CIN) has expanded dramatically as a result of systematic screens across yeast mutant arrays. Here we describe a comprehensive summary of the original Ctf genetic screen...
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