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Article

Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.

BMC systems biology - 6 Oct 2011

Svensson J Peter, Pesudo Laia Quirós, Fry Rebecca C, Adeleye Yeyejide A, Carmichael Paul, Samson Leona D

Abstract excerpt

BACKGROUND: A myriad of new chemicals has been introduced into our environment and exposure to these agents can damage cells and induce cytotoxicity through different mechanisms, including damaging DNA directly. Analysis of global transcriptional and phenotypic responses in the yeast S. cerevisiae provides means to identify pathways of damage recovery upon toxic exposure. RESULTS: Here we present a phenotypic...

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Identifiers

PMID: 21978764
DOI: 10.1186/1752-0509-5-157
PMCID: PMC3213080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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