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Article

Low MBL-associated serine protease 2 (MASP-2) levels correlate with urogenital schistosomiasis in Nigerian children.

Tropical medicine & international health : TM & IH - 1 Oct 2015

Ojurongbe Olusola, Antony Justin S, Van Tong Hoang, Meyer Christian G, Akindele Akeem A, Sina-Agbaje Olawumi R, Kremsner Peter G, Velavan Thirumalaisamy P

Abstract excerpt

OBJECTIVES: The human mannose-binding lectin (MBL) and ficolins (FCN) are involved in pathogen recognition in the first line of defence. They support activation of the complement lectin cascade in the presence of MBL-associated serine protease 2 (MASP-2), a protein that cleaves the C4 and C2 complement components. Recent studies found that distinct MBL2 and FCN2 promoter variants and their corresponding serum...

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Source

Identifiers

PMID: 26046446
DOI: 10.1111/tmi.12551

Genes

MASP2
FCN2
MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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