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Article

Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children.

Tissue antigens - 1 Oct 2009

Vallès X, Sarrias M-R, Casals F, Farnós M, Piñer R, Suárez B, Morais L, Mandomando I, Sigaúque B, Roca A, Alonso P L, Torres A, Thielens N M, Lozano F

Abstract excerpt

The mannose-binding lectin (MBL) pathway of complement system is activated when carbohydrate-bound MBL forms complexes with different serine proteases (MASP-1, MASP-2 and MASP-3), among which MASP-2 has a predominant functional role. Polymorphisms impairing the quantity and/or the functional activity of proteins encoded by the MBL2 and MASP2 genes have been reported in all human populations showing different...

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Source

Identifiers

PMID: 19775369
DOI: 10.1111/j.1399-0039.2009.01328.x

Genes

MASP2
MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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