Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria.

Malaria journal - 2 Mar 2012

Holmberg Ville, Onkamo Päivi, Lahtela Elisa, Lahermo Päivi, Bedu-Addo George, Mockenhaupt Frank P, Meri Seppo

Abstract excerpt

BACKGROUND: Innate immunity plays a crucial role in the host defense against malaria including Plasmodium falciparum malaria in pregnancy, but the roles of the various underlying genes and mechanisms predisposing to the disease are poorly understood. METHODS: 98 single-nucletoide polymorphisms were genotyped in a set of 17 functionally related genes of the complement system in 145 primiparous Ghanaian women with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement Activation
Share to Complement System Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Malaria, Falciparum

Share to Mannose-Binding Lectin

Share to Mannose-Binding Protein-Associated Serine Proteases

Share to Placenta

Share to Pregnancy Complications, Parasitic

Source

Open in PubMed Open full text

Identifiers

PMID: 22380611
DOI: 10.1186/1475-2875-11-61
PMCID: PMC3320545

Genes

MASP2
MBL2
FCN2

Variants

rs12085877
rs1800451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria.PMID 22380611Read ↗

Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children.Semantic proximity Read ↗

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.Semantic proximity Read ↗

Novel MASP2 variants detected among North African and Sub-Saharan individuals.Semantic proximity Read ↗

Association of a new mannose-binding lectin variant with severe malaria in Gabonese children.Semantic proximity Read ↗

Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes.Semantic proximity Read ↗

Mannose-binding lectin and its genetic variants.Semantic proximity Read ↗

Mannose-binding lectin genetics: from A to Z.Semantic proximity Read ↗

Genetic polymorphisms of mannose-binding lectin do not influence placental malaria but are associated with preterm deliveries.Semantic proximity Read ↗

A journey through the lectin pathway of complement—<scp>MBL</scp> and beyondSemantic proximity Read ↗

Components of the lectin pathway of complement activation in paediatric patients of intensive care units.Semantic proximity Read ↗

Mannose-binding lectin genotypes and pre-eclampsia: a case-control study.Semantic proximity Read ↗

MBL2 variations and malaria susceptibility in Indian populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.