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Article

Deficient serum mannose-binding lectin levels and MBL2 polymorphisms increase the risk of single and recurrent Cryptosporidium infections in young children.

The Journal of infectious diseases - 15 Nov 2009

Carmolli Marya, Duggal Priya, Haque Rashidul, Lindow Janet, Mondal Dinesh, Petri William A, Mourningstar Phoenix, Larsson Catherine J, Sreenivasan Meera, Khan Salwa, Kirkpatrick B D

Abstract excerpt

Mannose-binding lectin (MBL) is an evolutionarily conserved protein that functions in human innate immunity by binding to microbial surfaces and promoting opsonophagocytosis. MBL has been shown to bind to Cryptosporidium sporozoites, and earlier work has suggested that the protective role of MBL may be most important in childhood. We evaluated the association between polymorphisms in the MBL gene (MBL2), serum...

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Source

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Identifiers

PMID: 19827946
DOI: 10.1086/606013
PMCID: PMC3400050

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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