Article
Role of mannose-binding lectin deficiency in HIV-1 and schistosoma infections in a rural adult population in Zimbabwe.
PloS one - 1 Jan 2015
Zinyama-Gutsire Rutendo B L, Chasela Charles, Madsen Hans O, Rusakaniko Simbarashe, Kallestrup Per, Christiansen Michael, Gomo Exnevia, Ullum Henrik, Erikstrup Christian, Munyati Shungu, Kurewa Edith N, Stray-Pedersen Babill, Garred Peter, Mduluza Takafira
Abstract excerpt
BACKGROUND: Polymorphism in the MBL2 gene lead to MBL deficiency, which has been shown to increase susceptibility to various bacterial, viral and parasitic infections. We assessed role of MBL deficiency in HIV-1 and schistosoma infections in Zimbabwean adults enrolled in the Mupfure Schistosomiasis and HIV Cohort (MUSH Cohort). METHODS: HIV-1, S. haematobium and S. mansoni infections were determined at baseline....
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