Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mannose-binding lectin and MBL-associated serine protease-2 gene polymorphisms in a Brazilian population from Rio de Janeiro.

International journal of immunogenetics - 1 Feb 2012

Ferraroni N R, Segat L, Guimarães R L, Brandão L A C, Crovella S, Constantino-Silva R N, Loja C, da Silva Duarte A J, Grumach A S

Abstract excerpt

Mannose-binding lectin (MBL) is a protein able to bind to carbohydrate patterns on pathogen membranes; upon MBL binding, its' associated serine protease MBL-associated serine protease type 2 (MASP2) is autoactivated, promoting the activation of complement via the lectin pathway. For both MBL2 and MASP2 genes, the frequencies of polymorphisms are extremely variable between different ethnicities, and this aspect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Dyes

Share to Genetics, Population

Share to Genome, Human

Share to HapMap Project

Share to Mannose-Binding Lectin

Share to Mannose-Binding Protein-Associated Serine Proteases

Source

Identifiers

PMID: 22035380
DOI: 10.1111/j.1744-313X.2011.01052.x

Genes

MASP2
MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mannose-binding lectin and MBL-associated serine protease-2 gene polymorphisms in a Brazilian population from Rio de Janeiro.PMID 22035380Read ↗

Mannose-binding lectin and its genetic variants.Semantic proximity Read ↗

Genetic and structural analysis of MBL2 and MASP2 polymorphisms in south-eastern African children.Semantic proximity Read ↗

Characterization of mannose-binding lectin (MBL) variants by allele-specific sequencing of MBL2 and determination of serum MBL protein levels.Semantic proximity Read ↗

Mannose-binding lectin genetics: from A to Z.Semantic proximity Read ↗

Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphisms in the East Siberia and Russian Arctic populations.Semantic proximity Read ↗

Diversity of the MBL2 gene in various Brazilian populations and the case of selection at the mannose-binding lectin locus.Semantic proximity Read ↗

Mannose binding lectin and mannose binding lectin-associated serine protease-2 genes polymorphisms in human T-lymphotropic virus infection.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphisms in Brazilian patients with rheumatoid arthritis.Semantic proximity Read ↗

Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity.Semantic proximity Read ↗

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphisms in the East Siberia and Russian Arctic populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.