Article
Human body epigenome maps reveal noncanonical DNA methylation variation.
Nature - 9 Jul 2015
Schultz Matthew D, He Yupeng, Whitaker John W, Hariharan Manoj, Mukamel Eran A, Leung Danny, Rajagopal Nisha, Nery Joseph R, Urich Mark A, Chen Huaming, Lin Shin, Lin Yiing, Jung Inkyung, Schmitt Anthony D, Selvaraj Siddarth, Ren Bing, Sejnowski Terrence J, Wang Wei, Ecker Joseph R
Abstract excerpt
Understanding the diversity of human tissues is fundamental to disease and requires linking genetic information, which is identical in most of an individual's cells, with epigenetic mechanisms that could have tissue-specific roles. Surveys of DNA methylation in human tissues have established a complex landscape including both tissue-specific and invariant methylation patterns. Here we report high coverage...
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