Article

Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

2020-07-14

Abstract excerpt

<title>Abstract</title> <p>5-Hydroxymethylcytosine (5hmC) is an important epigenetic mark that regulates gene expression. Charting the landscape of 5hmC in human tissues is fundamental to understand its regulatory functions. Here, we systematically profiled the whole-genome 5hmC landscape at single-base resolution for 19 types of human tissues. We found that 5hmC preferentially decorates gene bodies and outperfor...

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Literature Corpus work: f00392a8-8b0b-53ed-ad68-72bd36f1e35d
DOI: 10.21203/rs.3.rs-39144/v1

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