Article

Spatiotemporal DNA Methylome Dynamics of the Developing Mammalian Fetus

2017-07-21

Abstract excerpt

<h4>Summary</h4> Genetic studies have revealed an essential role for cytosine DNA methylation in mammalian development. However, its spatiotemporal distribution in the developing embryo remains obscure. Here, we profiled the methylome landscapes of 12 mouse tissues/organs at 8 developmental stages spanning from early embryogenesis to birth. Indepth analysis of these spatiotemporal epigenome maps systematically de...

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Literature Corpus work: cfe49b8b-1548-5c13-bdf1-021ad775a0aa
DOI: 10.1101/166744

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