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Human panepigenome represents epigenomic diversity

2026-08-23

Abstract excerpt

The human pangenome captures genetic diversity beyond a single linear reference, yet conventional DNA methylome maps largely assume that the underlying CpG substrate is fixed. Here we present a first draft of the human panepigenome on DNA methylation, generated from 440 haplotype-resolved long-read methylomes spanning 26 globally distributed populations. This map jointly captures CpG presence, absence and methylat...

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Literature Corpus work
4819f31a-1401-58e3-a536-2640d9476e27
DOI
10.64898/2026.08.19.745838
Open publication

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Human panepigenome represents epigenomic diversityDOI 10.64898/2026.08.19.745838
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