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Article

Changes in Aβ biomarkers and associations with APOE genotype in 2 longitudinal cohorts.

Neurobiology of aging - 1 Aug 2015

Resnick Susan M, Bilgel Murat, Moghekar Abhay, An Yang, Cai Qing, Wang Mei-Cheng, Thambisetty Madhav, Prince Jerry L, Zhou Yun, Soldan Anja, Wong Dean F, O'Brien Richard J, Ferrucci Luigi, Albert Marilyn S

Abstract excerpt

Apolipoprotein E (APOE) genotype influences onset age of Alzheimer's disease but effects on disease progression are less clear. We investigated amyloid-β (Aβ) levels and change in relationship to APOE genotype, using 2 different measures of Aβ in 2 different longitudinal cohorts. Aβ accumulation was measured using positron emission tomography (PET) imaging and (11)C-Pittsburgh compound-B (PiB) in 113 Baltimore...

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Identifiers

PMID: 26004017
DOI: 10.1016/j.neurobiolaging.2015.04.001
PMCID: PMC5084914

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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