Article
Aβ amyloid, cognition, and APOE genotype in healthy older adults.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2013
Lim Yen Ying, Ellis Kathryn A, Ames David, Darby David, Harrington Karra, Martins Ralph N, Masters Colin L, Rowe Christopher, Savage Greg, Szoeke Cassandra, Villemagne Victor L, Maruff Paul
Abstract excerpt
BACKGROUND: Only one study has investigated the relationship between cerebral β-amyloid (Aβ), apolipoprotein E (APOE) ε4 genotype, and cognition. Although significant relationships between cerebral Aβ and cognition were observed in ε4 carriers but not noncarriers, the magnitude of this relationship was not reported. Further, when demographic variables were controlled, the influence of APOE ε4 on the relationship...
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