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Article

APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging.

Annals of neurology - 1 Jan 2010

Morris John C, Roe Catherine M, Xiong Chengjie, Fagan Anne M, Goate Alison M, Holtzman David M, Mintun Mark A

Abstract excerpt

OBJECTIVE: To examine interactions of apolipoprotein E (APOE) genotype with age and with in vivo measures of preclinical Alzheimer disease (AD) in cognitively normal aging. METHODS: Two hundred forty-one cognitively normal individuals, aged 45-88 years, had cerebral amyloid imaging studies with P...

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Identifiers

PMID: 20186853
DOI: 10.1002/ana.21843
PMCID: PMC2830375

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20186853-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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