Article
Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics.
Current opinion in rheumatology - 1 Jul 2015
Ombrello Michael J, Kastner Daniel L, Remmers Elaine F
Abstract excerpt
PURPOSE OF REVIEW: This article will review the genetic evidence implicating ERAP1, which encodes the endoplasmic reticulum-associated amino-peptidase 1, in susceptibility to rheumatic disease. RECENT FINDINGS: Genetic variants and haplotypes of ERAP1 are associated with AS, psoriasis, and Behçet's disease in people of varying ancestries. In each of these diseases, disease-associated variants of ERAP1 have been...
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