Article
The role of polymorphic ERAP1 in autoinflammatory disease.
Bioscience reports - 3 Sept 2018
Reeves Emma, James Edward
Abstract excerpt
Autoimmune and autoinflammatory conditions represent a group of disorders characterized by self-directed tissue damage due to aberrant changes in innate and adaptive immune responses. These disorders possess widely varying clinical phenotypes and etiology; however, they share a number of similarities in genetic associations and environmental influences. Whilst the pathogenic mechanisms of disease remain poorly...
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