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Article

ERAP1 in ankylosing spondylitis: genetics, biology and pathogenetic role.

Current opinion in rheumatology - 1 Jul 2013

Alvarez-Navarro Carlos, López de Castro José A

Abstract excerpt

PURPOSE OF REVIEW: Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an aminopeptidase of the endoplasmic reticulum involved in trimming of peptides to their optimal size for binding to major histocompatibility complex class I molecules. Natural ERAP1 polymorphism resulting in altered enzymatic a...

Read the complete abstract on PubMed

Topics

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Share to Aminopeptidases
Share to ERAP1 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B27 Antigen

Share to Minor Histocompatibility Antigens

Share to Polymorphism, Genetic

Share to Spondylitis, Ankylosing

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 23656713
DOI: 10.1097/BOR.0b013e328362042f

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23656713-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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