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Article

Prodomain removal enables neto to stabilize glutamate receptors at the Drosophila neuromuscular junction.

PLoS genetics - 1 Jan 2015

Kim Young-Jun, Igiesuorobo Oghomwen, Ramos Cathy I, Bao Hong, Zhang Bing, Serpe Mihaela

Abstract excerpt

Stabilization of neurotransmitter receptors at postsynaptic specializations is a key step in the assembly of functional synapses. Drosophila Neto (Neuropillin and Tolloid-like protein) is an essential auxiliary subunit of ionotropic glutamate receptor (iGluR) complexes required for the iGluRs clustering at the neuromuscular junction (NMJ). Here we show that optimal levels of Neto are crucial for stabilization of...

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Identifiers

PMID: 25723514
DOI: 10.1371/journal.pgen.1004988
PMCID: PMC4344203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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