Article
A perisynaptic ménage à trois between Dlg, DLin-7, and Metro controls proper organization of Drosophila synaptic junctions.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Apr 2010
Bachmann André, Kobler Oliver, Kittel Robert J, Wichmann Carolin, Sierralta Jimena, Sigrist Stephan J, Gundelfinger Eckart D, Knust Elisabeth, Thomas Ulrich
Abstract excerpt
Structural plasticity of synaptic junctions is a prerequisite to achieve and modulate connectivity within nervous systems, e.g., during learning and memory formation. It demands adequate backup systems that allow remodeling while retaining sufficient stability to prevent unwanted synaptic disintegration. The strength of submembranous scaffold complexes, which are fundamental to the architecture of synaptic...
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