Article
Functional reconstitution of Drosophila melanogaster NMJ glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America - 12 May 2015
Han Tae Hee, Dharkar Poorva, Mayer Mark L, Serpe Mihaela
Abstract excerpt
The Drosophila larval neuromuscular junction (NMJ), at which glutamate acts as the excitatory neurotransmitter, is a widely used model for genetic analysis of synapse function and development. Despite decades of study, the inability to reconstitute NMJ glutamate receptor function using heterologous expression systems has complicated the analysis of receptor function, such that it is difficult to resolve the...
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