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Article

PP2A and GSK-3beta act antagonistically to regulate active zone development.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Sept 2009

Viquez Natasha M, Füger Petra, Valakh Vera, Daniels Richard W, Rasse Tobias M, DiAntonio Aaron

Abstract excerpt

The synapse is composed of an active zone apposed to a postsynaptic cluster of neurotransmitter receptors. Each Drosophila neuromuscular junction comprises hundreds of such individual release sites apposed to clusters of glutamate receptors. Here, we show that protein phosphatase 2A (PP2A) is required for the development of structurally normal active zones opposite glutamate receptors. When PP2A is inhibited...

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Source

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Identifiers

PMID: 19759297
DOI: 10.1523/JNEUROSCI.5584-08.2009
PMCID: PMC2776049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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