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Article

Assessment of the frequency of the transforming growth factor beta-1 sequence polymorphisms in patients with alcohol dependence syndrome.

Acta biochimica Polonica - 1 Jan 2015

Augustyńska Beata, Araszkiewicz Aleksander, Woźniak Marcin, Grzybowski Tomasz, Skonieczna Katarzyna, Woźniak Alina, Żyła Magdalena

Abstract excerpt

Alcohol abuse is one of the most significant factors in the development of liver fibrosis. The pathomechanism of liver fibrosis is the same regardless of its etiology. Fibrosis is a sign of an imbalance between the synthesis of the extracellular matrix components and their degradation. Among the many cytokines that affect hepatic stellate cell activation it seems that transforming growth factor beta (TGF-β) is...

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PMID: 25710054
DOI: 10.18388/abp.2014_772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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