Article
Polymorphisms in the interleukin-10 gene promoter and the risk of alcoholism and alcoholic liver disease in Caucasian Spaniard men.
Alcohol (Fayetteville, N.Y.) - 1 May 2010
Auguet Teresa, Vidal Francesc, Broch Montserrat, Olona Montserrat, Aguilar Carmen, Morancho Beatriz, López-Dupla Miguel, Quer Joan-Carles, Sirvent Joan-Josep, Richart Cristóbal
Abstract excerpt
Controversy surrounds the possible influence of the single nucleotide polymorphisms (SNPs) of the interleukin-10 (IL-10) gene promoter on the risk for alcoholic liver disease. Our aim was to determine whether the SNP of the IL-10 gene promoter are associated with an increased risk for alcoholism and for alcoholic liver disease in male Spaniards. The -627 C>A SNP of the IL-10 gene promoter was assessed in a cohort...
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